Do you notice your skin feeling duller, drier, and thinner, and are you looking for a treatment that truly restores rather than simply fills? Polynucleotides are a biostimulator that improves your skin quality from within. The result is subtle and respectful: a fitter, better-hydrated complexion that suits you. On this page you'll read what polynucleotides exactly do, who they are suitable for and when they're not, how a treatment works at Dr T. in Ghent, and what you can expect in terms of results and timing.
Polynucleotides are small fragments of purified DNA, usually derived from fish sources, that are very well tolerated by your skin. They are introduced into the skin through fine micro-injections and act as a biostimulator: they encourage your own skin cells to repair more actively.
The difference with classic fillers is important. A filler mechanically adds volume, while polynucleotides mainly improve your skin quality. They attract moisture, support the production of collagen and elastin, and help your skin become firmer, smoother, and better hydrated.
Therefore, polynucleotides are not a treatment for those who want more volume or defined contours, but for those who want to improve the overall condition of the skin. The effect is cumulative and natural, not obvious or forced.
Polynucleotides are interesting if your skin has become duller, drier, or thinner, if you see fine lines and a tired-looking complexion, or if you want to strengthen a fragile, dark area around the eyes. They can also be a good choice for the neck, face, and overall skin quality.
They are often a good step for those who do not yet need volume, but want to do something for the foundation of the skin. Sometimes they also fit into a broader plan, alongside for example Profhilo or biostimulators, depending on what your skin needs at that moment.
Honestly: not everyone is a suitable candidate. In case of an active skin infection or inflammation in the treatment area, with certain autoimmune conditions, or with a known allergy to fish components, this treatment is better postponed or not performed. During pregnancy or breastfeeding, we never treat. During your consultation, Dr T. assesses whether polynucleotides truly suit you and your situation.
Everything starts with a consultation. Dr T. listens to what bothers you, examines your skin and your medical background, and honestly explains whether polynucleotides are the right choice or if another approach is better. You won't get a sales pitch, but evidence-based advice.
The treatment itself is done with very fine needles, with which the product is applied at multiple points in the skin. A session typically doesn't last long and you can usually just continue your day afterwards.
For a good and stable result, multiple sessions are often needed, spread over several weeks. Dr T. works with you to set up a realistic schedule that fits your skin, your calendar, and your goal.
Polynucleotides work gradually, because they stimulate your own repair instead of immediately filling. You often notice the first improvement in hydration and skin feel after a few weeks, while firmness and overall skin quality continue to build as the treatment course progresses.
The result is intentionally subtle: a fresher, more supple, and better hydrated skin that looks calmer and healthier. You won't look different, you'll mainly look more rested. This aligns with Dr T.'s style, who aims for a natural and respectful result.
How long the effect lasts varies from person to person and depends on your skin, age, and lifestyle. A maintenance treatment after a while helps to preserve the result. What is realistic for you will be discussed during the consultation.
Polynucleotides are generally well tolerated. Still, mild, temporary reactions to the injections are normal: redness, slight swelling, tenderness, or an occasional bruise on the treated area. These usually disappear on their own within a few days.
Serious side effects are rare, especially when the treatment is performed by a doctor who thoroughly assesses you beforehand. That's why we value a thorough consultation, correct technique, and clear aftercare advice, such as letting the area rest and avoiding intense heat or sun for the first few days.
Do you have a known allergy, are you taking certain medications, or do you doubt your suitability? Tell us in advance, so that Dr T. can safely and honestly assess whether polynucleotides are a responsible choice for you.
The price of a polynucleotide treatment cannot be captured in a fixed amount. It depends on the treated area, the number of sessions your skin needs, and the type of product that is most suitable in your situation.
That's why Dr T. does not work with empty promises or standard rates that are separate from your skin. During the consultation, you'll get an honest estimate of what to expect, so you can make an informed choice without surprises afterwards.
Want to know if polynucleotides are suitable for your skin, and what it would cost in your case? Then feel free to book a consultation with Dr T. in Ghent. You'll receive a calm assessment and advice that is genuinely in your interest.
Book a personal consultation with Dr T.
Make an appointmentRegenerative treatments all have the same goal: to strengthen your skin from the inside out, not just mask it. Yet the route differs. Polynucleotides are short DNA fragments that stimulate fibroblasts to tissue repair and moisture binding, ideal for thin, fragile skin or after damage from sun or laser. Sculptra works deeper in the subcutaneous layer as a collagen stimulator that rebuilds lost volume over months, making it excellent for loss of contour and firmness. Skin boosters, on the other hand, are ultra-thin hyaluronic acid preparations that intensely hydrate and improve skin elasticity without volume increase. At Dr T., we not only consider what you want to achieve, but also what your skin biologist needs: a powerful tissue repair stimulator, a deep collagen booster, or a hydration upgrade.
For those who doubt between biostimulation and a classic filler: a filler locally adds volume, while polynucleotides and Sculptra improve the architecture of your skin. That explains why the result comes gradually and looks natural, no one notices you had a treatment, but everyone sees you looking fresher.
Your comfort and a safe result are central. A typical session starts with thorough cleansing and disinfection of the skin. Feel free to come without make-up, that saves time.
I administer polynucleotides through a series of superficial injections with an ultra-fine needle or cannula, depending on the area (face, neck, décolleté, hands). The treatment usually lasts twenty to thirty minutes. Immediately afterwards, the skin may be slightly red and show small papules, which is a normal sign that the product is being absorbed. Within a few hours to a day, these traces fade. You can shower the same day, but sauna, intense sports, and direct sun are better avoided for 48 hours. After a few weeks, your skin feels softer, fuller, and more resilient; the real repair work happens calmly.
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