Discover how regenerative techniques such as biostimulation, PRP and collagen stimulators strengthen your skin from within, in a way no one can see, yet everyone notices.

A natural approach combines biostimulation, collagen stimulation and strengthening the skin from within. Treatments such as PRP, Sculptra and skin-improving injectables strengthen your own tissue, so wrinkles fade subtly without your face looking 'done'. The right choice depends on your skin type, age and specific concerns; a personalised plan gives the most natural result.
Wrinkles are a normal part of ageing, but that does not mean you have to accept them without question. Today there are many ways to soften lines and folds without resorting to surgery or an unnatural 'overfilled' effect. The key lies in treatments that prompt your body to repair itself. Think of biostimulation with PRP (platelet-rich plasma), collagen stimulators such as Sculptra, or targeted skin boosters that restore deep hydration and resilience. In this guide you will discover what really works, and why a tailored approach with Dr. Thierry De Smedt makes the difference.
Many people immediately think of botox or fillers when it comes to wrinkle treatments, but a natural result takes more than just an injection. It is about strengthening your own skin, so you look fresher without anyone being able to point out exactly what has changed. At Dr. Thierry De Smedt's practice, we start from your unique face, not from a standard treatment. With a background in surgery and years of experience in aesthetic medicine, he deliberately chooses regenerative techniques that breathe new life into your skin from within.
Biostimulation is the secret behind the most natural rejuvenation. Instead of simply filling wrinkles, you prompt the body to produce collagen and elastin itself. These are the building blocks of firm, smooth skin. Treatments such as Sculptra and PRP work deep in the skin layers and give a gradual, long-lasting effect. You will not see a dramatic difference overnight; you simply notice that your skin becomes fuller, firmer and more even. That is exactly what makes the result so believable.
Wrinkles are the result of a combination of factors. Intrinsic ageing slows down cell division and collagen production, while external influences such as UV radiation, smoking and pollution damage the skin. In addition, repeated muscle movements cause dynamic wrinkles, such as crow's feet and frown lines. Static wrinkles remain visible, even at rest. An effective approach tackles all of these elements: protection from the sun, good skincare at home, and treatments that work more deeply where needed. No cream can make wrinkles disappear completely, but ingredients such as retinol (vitamin A) can reduce fine lines. For deeper wrinkles, medical treatments offer the best results.
Not every wrinkle calls for the same approach. That is why, at Dr T.'s practice, we first look at your whole face, your skin type and your wishes. These are the main pillars:
This is how the main treatments compare:
| Treatment | Primary goal | Results visible | Duration of result | Best for | Not ideal for |
|---|---|---|---|---|---|
| Neurotoxins | Softening muscle activity | After a few hours to 3 days | On average 3 to 4 months | Frown lines, forehead lines, crow's feet | Deep static folds |
| Hyaluronic acid fillers | Filling and shaping | Immediately | 9 to 24 months: lips and tear trough 9 to 12 months, cheeks 18 to 24 months | Cheeks, tear trough, marionette lines, lip contour | Overactive muscle lines |
| Skinbooster | Hydration and skin quality | A few days | 4 to 6 months | Fine lines and dull skin | Deep volume loss |
| Sculptra biostimulator | Collagen stimulation and subtle lift | Gradually over weeks | On average 2 years, often longer | Jawline, cheeks, overall firmness | The T-zone: forehead, eyes, nose and around the mouth |
Alongside a treatment, a good daily routine is essential. Sun protection (at least SPF30) is the most effective anti-ageing measure. Add a retinol serum to speed up cell renewal and choose a moisturiser that suits your skin type. Exfoliating (once or twice a week) helps remove dead skin cells, so the skin looks smoother. But be critical: home remedies such as toothpaste or lemon juice do more harm than good, and 'wrinkles gone in 7 minutes' is simply not true. Real improvement takes time and a combination of the right treatments.
Persistent myths circulate on the internet. Toothpaste for wrinkles? At most it dries out the skin and can cause irritation. Grandma's home-remedy tips often recommend Vaseline or cucumber: good for hydration, but no miracle cure. Retinol is a proven active ingredient, but only in the right concentration and with guidance. If you want real results, choose treatments that are scientifically supported and performed by an experienced doctor.
At Dr. Thierry De Smedt's practice, safety comes first. We deliberately choose techniques with proven added value and always give you clear aftercare instructions, so you know exactly what to do and what to avoid. On the day of your treatment, avoid intense exercise and the sauna. Cooling is fine, but do not rub or press on the treated area. Some mild redness or swelling may occur, but this usually subsides quickly. If you do notice something you are unsure about, you can always come back for an evaluation or adjustment. That way your result stays subtle and balanced.
The exact price depends on the indication, the dosage and the chosen technique. The guide prices below give you an indication. How long a session takes depends on the technique (see the table), and during your consultation you receive a personal estimate tailored to your situation and wishes.
| Treatment | Indicative price | Treatment time | Result visible | Estimated duration | Remarks |
|---|---|---|---|---|---|
| Neurotoxins | 180 to 350 euros per area | 10 to 20 min | After a few hours to 3 days | On average 3 to 4 months | Mainly for frown lines, forehead lines and crow's feet |
| Hyaluronic acid fillers | 300 to 450 euros per ml | 20 to 45 min, depending on the area | Immediately | 9 to 24 months | Lips and tear trough 9 to 12 months, cheeks 18 to 24 months |
| Skinbooster | 250 to 350 euros per session | 15 to 30 min | A few days | 4 to 6 months | Focus on hydration and skin quality |
| Sculptra | 550 euros per vial | 20 to 30 min | Gradually | On average 2 years, often longer | Not in the T-zone |
Alongside a treatment, you can make a big difference yourself at home. With a few simple habits, you keep wrinkles at bay for longer and support the effect of your treatment.
Why choose Dr. Thierry De Smedt
My approach rests on two pillars: in-depth knowledge of the face from my surgical background, and boundless respect for your natural appearance. That is why I deliberately choose treatments that put your own body to work.
I work with biostimulation and collagen stimulators such as Sculptra and PRP, which strengthen and renew your skin instead of just filling it.
Every treatment is aimed at a natural refresh. Your face stays your face, just more rested, fresher and more harmonious.
No two faces are the same. During an extensive consultation, we decide together on the best combination for your skin and wishes.
Because we stimulate your own cell activity, the results are not only natural but also durable.
Does this sound familiar?
People often come to me not asking for a specific treatment, but with a feeling. That tired look, the sagging volume, the deeper lines that make you look older than you feel. Here are some situations we can resolve together.
This is often due to loss of volume or hydration. With skinboosters, PRP or a subtle filler treatment, we restore freshness.
Collagen loss makes the skin slacken. Sculptra or thread lifting can restore firmness and lift without surgery.
Dynamic wrinkles respond very well to a light dose of botox, so your expression is preserved while the lines soften.
A combination of botox and a skin-improving treatment gives your eyes back their openness, without anyone seeing exactly what has been done.
Frequently asked questions
Together we decide on a plan that suits your skin, age and life. <strong>Book an appointment today</strong> for a personal consultation with Dr. Thierry De Smedt in Ghent and discover how a natural approach can reduce your wrinkles.
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